I have adblock disabled.
Any time I click on anything, it throws a pop-up in my face. I understand you have to support the site, but you're only driving away people with things like this. I'm going to have to start google searching tags plus inurl:gelbooru.
I'll check back in a week, if it's still the way it is now, I can't use this site any more.

With cookies enabled, it should only show up once.

Anything that blocks scripts from running will cause the popups, not just adblock. This includes script blockers like NoScript and uMatrix, as well as userscripts that may interfere with our scripts' operation and custom user themes that hide elements on the page, as these will also prevent the JavaScript from running.

It may sound strange, but mac & cheese is actually one of my favorite foods. Dickey's Barbecue Pit sells a meal called the Beefy Mac Stack, which is basically brisket piled on top of mac & cheese, and it's one of my favorite meals when I eat out at work. It's surprisingly affordable for how much food you get, too. If it weren't 2:31AM, I'd seriously consider going out for it right now just thinking about it.

It's not an adblock issue. Without it there's still tons of pop ups. Far more than there should be.

I've noticed a lot of novelty macaroni and cheese meals in the frozen dinner section of the grocery store. On one hand, it's pretty interesting getting to try the different flavors. On the other hand, at that point it isn't really mac and cheese. There's a limit to what you can do with mac and cheese and have it still be mac and cheese. Usually I only add fresh course ground black pepper.