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NIGA Nurses were developed by the Royal Hospital Female Body Laboratory. The entire project lasted five years. Although the principle of NIGA seems simple, the actual R&D proved more difficult. The key problem was maintaining cognitive ability and preventing muscle degeneration during the long periods of confinement. The human brain constantly needs to deal with external information – this is the key to maintaining a standard level of cognitive ability. If it is kept in an isolated state for too long, it will start to degenerate, possibly even leading to a mental breakdown. Meanwhile, the body's muscles will atrophy due to the inactivity.

The NIGA Nurses are kept in a state of continuous climax inside the closed box. A dual-piston system is installed at the back of the box which allows high velocity insertion of alternating pistons into the vagina, at a frequency of up to 3.5 insertions per second.
When a woman orgasms, if the state of euphoria is strong enough, higher brain functionality is temporarily suspended for a brief period. Additionally, the muscular contractions that accompany the climax are strong enough to prevent atrophy without requiring a large exercise space. Therefore, as long as climax can be reached frequently enough, it can effectively prevent the mental breakdown and muscular atrophy caused by extended confinement.

Of course it is not possible for a woman's body to naturally sustain a state of continuous orgasm over a period of several months – for this reason the Female Body Laboratory adds specific neurological drugs to the nutrient bottle. These drugs are not simple aphrodisiac hormones. Instead, it allows the brain to bypass the normal post-orgasmic recovery period, meaning the female body can continue to respond positively to external sexual stimulation, even after the most violent orgasm. In this way, they can continue to climax repeatedly, effectively removing the upper limit to the number of consecutive orgasms that can be achieved.

The Vita Box monitors its occupant's physical condition. Whenever it detects that she is in a non-sleeping state, it automatically engages the high-speed piston system, allowing her to quickly achieve orgasm.

Interestingly, NIGA Nurses are not fed through the mouth during containment – instead, a nutrient-rich fluid is inserted anally.
First, the fluid is fed into her through hydraulic pressure. It sits in her intestinal tract for half an hour, at which point a second batch of fluid is fed into the intestines. This causes the first batch to enter the stomach. After another half-hour period, the hydraulic pressure from the rear forces the fluid to be excreted through the mouth.
Because after a single cycle the fluid is still likely to contain a high proportion of undigested nutrients, it is filtered then reinserted into the nutrient bottle. From there, it will be reinserted into the girl's body as part of the next feeding cycle.

The lower part of the mouth tube –seen here– has a tongue-root depressor that can help induce vomiting, aiding excretion through the mouth.

Although the side effects of the nerve drugs used by NIGA Nurses are small in comparison to those of other aphrodisiacs, the burden of continued orgasm on their bodies is still enormous. This hidden injury can seriously damage her normal metabolism. For this reason, each nurse can only be used for a period of three years - although exceeding this period is not fatal, it may impact her physical condition sufficiently that she can no longer engage in nursing work. For this reason, the after-sales service will provide replacement nurses to customers for free.

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